Amyloidosis Alliance The Voice of Patients

Research

Clinical trials

Every amyloidosis study now recruiting, about to open, or enrolling by invitation, anywhere in the world, listed straight from ClinicalTrials.gov and refreshed every day.

Information, not medical advice. The Alliance does not run these studies and cannot enrol you in one. If a trial looks relevant, discuss it with the doctor who follows your amyloidosis.

Recruiting and upcoming studies

The list covers AL, ATTR and AA amyloidosis as well as cerebral amyloid angiopathy. Each card says where the study stands: open to anyone who meets its criteria, not yet open, or restricted to people the investigators invite. Studies that close simply leave the list.

Showing 49–60 of 202 trials

RecruitingNot specified

Pan-Amyloid PET/CT in Various Amyloid-Related Disease (opens on ClinicalTrials.gov)

To evaluate the potential usefulness of 18F-92/AV45/TPZA/FT8, 11C-PIB positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various Pan-Amyloid-related…

Study
Observational (registry, imaging)
Sponsor
Tianjin Medical University

Recruiting in: China

NCT07130565Updated 8 September 2026

RecruitingNot specified

Echocardiographic Characterization of Cardiac Amyloidosis (opens on ClinicalTrials.gov)

This is a mono-center observational ambispective study in which patients with cardiac amyloidosis evaluated at the Fondazione Policlinico Universitario Agostino Gemelli IRCCS (Rome, Italy)…

Study
Observational (registry, imaging)
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Recruiting in: Italy

NCT05760287Updated 4 September 2026

RecruitingNot specified

Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis – Evaluation Using Echocardiography, Computed Tomography, Tc99-SPECT/CT and Cardiac Magnetic Resonance Imaging (CMR) (opens on ClinicalTrials.gov)

Degenerative aortic stenosis (AS) is frequently accompanied by left ventricular hypertrophy and diastolic dysfunction, features that overlap with transthyretin (ATTR) cardiac amyloidosis. Because concomitant…

Study
Observational (registry, imaging)
Sponsor
University Hospital Tuebingen

Recruiting in: Germany

NCT07752732Updated 2 September 2026

Not yet recruitingATTR (transthyretin)

An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of ALXN2220 in Adults With Transthyretin Amyloid Cardiomyopathy (opens on ClinicalTrials.gov)

The purpose of Study ALXN2220-ATTRCM-302 is to evaluate the long-term safety, tolerability and efficacy of ALXN2220 in adult participants with ATTR-CM treated with ALXN2220…

Study
Interventional (treatment)
Phase
Phase 3
Sponsor
Alexion Pharmaceuticals, Inc.

Recruiting in: ArgentinaAustraliaAustriaBelgium+23

NCT07789483Updated 28 August 2026

RecruitingCerebral amyloid angiopathy

Application of Digital Twins’ Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project) (opens on ClinicalTrials.gov)

The goal of this clinical trial is to obtain initial feedback on the implementation of the STRATIF-AI platform and digital twin in the secondary…

Study
Interventional (treatment)
Sponsor
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Recruiting in: Italy

NCT06714097Updated 28 August 2026

Not yet recruitingAL (light chain)

Study to Evaluate Change in Disease Activity and Adverse Events of Subcutaneous Etentamig Compared With Daratumumab Plus Cyclophosphamide Plus Bortezomib Plus Dexamethasone (Dara-CyBorD) in Adults With Amyloid Light Chain (AL) Amyloidosis (opens on ClinicalTrials.gov)

Amyloid light chain (AL) amyloidosis is a rare disease caused by abnormal plasma cells producing misfolded light chain proteins that deposit in organs, leading…

Study
Interventional (treatment)
Phase
Phase 3
Sponsor
AbbVie

No study locations listed yet

NCT07793422Updated 28 August 2026

This list only covers amyloidosis studies that are open or about to open. The registry holds every study, including those already completed.

Search all studies on ClinicalTrials.gov (opens in a new tab)

Source: ClinicalTrials.gov (U.S. National Library of Medicine). List last retrieved on 7 November 2026. clinicaltrials.gov

Not sure where to start?

Our member associations know the teams running these studies in their own country, and can help you prepare the conversation with your doctor.

Find an association near you
Contact the Alliance