Research
Clinical trials
Every amyloidosis study now recruiting, about to open, or enrolling by invitation, anywhere in the world, listed straight from ClinicalTrials.gov and refreshed every day.
Information, not medical advice. The Alliance does not run these studies and cannot enrol you in one. If a trial looks relevant, discuss it with the doctor who follows your amyloidosis.

Recruiting and upcoming studies
The list covers AL, ATTR and AA amyloidosis as well as cerebral amyloid angiopathy. Each card says where the study stands: open to anyone who meets its criteria, not yet open, or restricted to people the investigators invite. Studies that close simply leave the list.
Showing 121–132 of 202 trials
RecruitingAL (light chain)
A Registry of AL Amyloidosis (ReAL) (opens on ClinicalTrials.gov)
The purpose of this protocol is to generate a large registry of patients with AL amyloidosis.
- Study
- Observational (registry, imaging)
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Recruiting in: Italy
NCT04839003Updated 16 April 2026
RecruitingNot specified
A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation (opens on ClinicalTrials.gov)
The purpose of this study is to deploy and evaluate informational AI-Echo algorithms that assist echo clinicians in interpreting core echocardiographic parameters (e.g., LV/RV…
- Study
- Observational (registry, imaging)
- Sponsor
- Mayo Clinic
Recruiting in: United States
NCT07308704Updated 16 April 2026
RecruitingATTR (transthyretin)
NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis (opens on ClinicalTrials.gov)
All ATTRwt patients on tafamidis 61 mg treatment will be clinically evaluated before treatment initiation and subsequently every six months for the eligibility to…
- Study
- Observational (registry, imaging)
- Sponsor
- Paolo Milani
Recruiting in: Italy
NCT06251778Updated 16 April 2026
RecruitingAL (light chain)
Promoting Diagnosis and Management of AL in Italy (ProDigALIty) (opens on ClinicalTrials.gov)
The investigators plan to establish a dedicated network of Italian Hematologic Departments interconnected with the Amyloidosis Research and Treatment Center in Pavia to: 1.…
- Study
- Observational (registry, imaging)
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Recruiting in: Italy
NCT06383143Updated 16 April 2026
RecruitingATTR (transthyretin)
A Research Study to Look at the Distribution and Effects of Coramitug on Amyloid Deposits in Heart Tissue Using PET/CT Imaging in People With ATTR Amyloidosis. (opens on ClinicalTrials.gov)
The study is conducted in participants with Transthyretin Amyloid Cardiomyopathy (ATTR-CM), a heart disease that occurs in people with the disease ATTR amyloidosis. The…
- Study
- Interventional (treatment)
- Phase
- Phase 1
- Sponsor
- Novo Nordisk A/S
Recruiting in: Netherlands
NCT07448623Updated 13 April 2026
RecruitingATTR (transthyretin)
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis (opens on ClinicalTrials.gov)
This is a single center prospective study evaluating 124I-evuzumitide in patients with systemic amyloidosis. The purpose of this study is to 1) Establish the…
- Study
- Interventional (treatment)
- Phase
- Phase 2
- Sponsor
- Oregon Health and Science University
Recruiting in: United States
NCT05758493Updated 13 April 2026
RecruitingATTR (transthyretin)
Phenotypic Manifestations of Hereditary ATTR Amyloidosis (opens on ClinicalTrials.gov)
This study focuses on hereditary transthyretin amyloidosis (ATTRv) with the Val50Met variant in a non endemic aerea
- Study
- Observational (registry, imaging)
- Sponsor
- Hospital 9 de Julio de Las Breñas
Recruiting in: Argentina
NCT07124377Updated 2 April 2026
Not yet recruitingNot specified
CAR-NK Therapy for Cardiac Amyloidosis (opens on ClinicalTrials.gov)
Relapsed/refractory (R/R) light chain cardiac amyloidosis is associated with a poor prognosis, and cellular immunotherapy constitutes a crucial therapeutic modality for these patients. The…
- Study
- Interventional (treatment)
- Phase
- Phase 1
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
No study locations listed yet
NCT07504289Updated 31 March 2026
RecruitingCerebral amyloid angiopathy
SEarchiNg biomarkErs Cerebral Amyloid Angiopathy (SENECA) (opens on ClinicalTrials.gov)
Cerebral amyloid angiopathy (CAA) is one of the major types of cerebral small vessel disease, and a leading cause of spontaneous intracerebral hemorrhage and…
- Study
- Observational (registry, imaging)
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Recruiting in: Italy
NCT04204642Updated 30 March 2026
RecruitingATTR (transthyretin)
The Italian Transthyretin Amyloidosis Web-Network (opens on ClinicalTrials.gov)
The study aims, by generating a large registry of patients with ATTR amyloidosis, including data at diagnosis and during follow up, to describe the…
- Study
- Observational (registry, imaging)
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Recruiting in: Italy
NCT05444920Updated 27 March 2026
RecruitingATTR (transthyretin)
Comprehensive Program for Hereditary Transthyretin Amyloidosis (opens on ClinicalTrials.gov)
The Comprehensive Program for Hereditary Transthyretin Amyloidosis describes a prospective observational study focused on understanding hereditary transthyretin amyloidosis (ATTR), a progressive and potentially fatal…
- Study
- Observational (registry, imaging)
- Sponsor
- Hospital de Alta Complejidad en Red
Recruiting in: Argentina
NCT07213297Updated 24 March 2026
RecruitingAL (light chain)
Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource (opens on ClinicalTrials.gov)
The investigators are researching patients with diseases of their plasma cells in order to improve their quality and length of life. The investigators have…
- Study
- Observational (registry, imaging)
- Sponsor
- Ohio State University Comprehensive Cancer Center
Recruiting in: United States
NCT01408225Updated 23 March 2026
This list only covers amyloidosis studies that are open or about to open. The registry holds every study, including those already completed.
Source: ClinicalTrials.gov (U.S. National Library of Medicine). List last retrieved on 7 November 2026. clinicaltrials.gov
Not sure where to start?
Our member associations know the teams running these studies in their own country, and can help you prepare the conversation with your doctor.